Lorenzen Cancer Foundation Urges Cancer Drug Coverage in the Prescription Drug Benefit Act

In the interests of cancer patients and oncologists nationwide, the Lorenzen Cancer Foundation (LCF), a non-profit dedicated to fighting pancreatic cancer, has joined the public interest law firm Washington Legal Foundation (WLF) and others today in presenting a written comments statement to the U.S. Centers for Medicare and Medicaid Services (CMS) voicing support for the Section 641 demonstration project and expressing concerns regarding CMS’s proposed restrictions limiting coverage of the drug benefit to exclude off-label uses of FDA-approved drug or biological therapies.

Monterey, CA July 7, 2004 -- In the interests of cancer patients and oncologists nationwide, the Lorenzen Cancer Foundation (LCF), a non-profit dedicated to fighting pancreatic cancer, has joined the public interest law firm Washington Legal Foundation (WLF) and others today in presenting a written comments statement to the U.S. Centers for Medicare and Medicaid Services (CMS) voicing support for the Section 641 demonstration project and expressing concerns regarding CMS’s proposed restrictions limiting coverage of the drug benefit to exclude off-label uses of FDA-approved drug or biological therapies.

Once the Food and Drug Administration approves a drug for marketing, physicians may prescribe the drug for purposes other than those that the FDA has given specific indication. Off-label prescribing is common in cancer treatment as drugs often work well for many types of cancer. A General Accounting Office analysis in 1991 demonstrated that over half of cancer patients received at least one off-label medicine in the course of their care.

In enacting Section 641 of the Medicare Prescription Drug and Modernization Act of 2003, Congress did not exclude off-label uses from the demonstration project related to Section 641. To the contrary, Section 641(a) directs that the project be conducted following the standards of the part D benefit program which does not exclude off-label use.

Recently announced proposed eligibility criteria by the CMS effectively exclude the coverage of off-label use of FDA-approved agents for cancer therapy and in other serious diseases.
   
Today’s statement urges CMS officials to reverse this position and to make clear to the public and to medical providers that Medicare will reimburse for off-label use for medications and biological therapies in the demonstration project related to Section 641. And further, to make clear that any proposed or actual restriction on off-label use in the demonstration project is not a precedent for full enactment of the part D prescription drug benefit program.

Pancreatic Cancer Facts:
· Pancreatic cancer is the most virulent of the major cancers
· Pancreatic cancer research is the least funded of the major cancers
· Pancreatic cancer causes more than 1% of all death in the U.S.
· Pancreatic cancer is the fourth most common cause of cancer mortality

How Diet Influences Cancer Risk

Posted by Vanhoten | 7:35 PM | | 0 comments »

Diet is a double edged sword. Improper diet increases the risk of cancer but a proper, well balanced diet reduces the cancer risk.

Diet is one of the most important lifestyle factors and has been estimated to account for up to 80% of cancers of the large bowel, breast, and prostate. Diet affects the risk of many other cancers, including cancers of the lung, prostate, stomach, esophagus and pancreas.

Prostate Cancer:
High consumption of meat, especially red meat, substantially increases the risk of prostate cancer.

Vegetables, especially cooked tomatoes, reduce the risk of prostate cancer. In one clinical trial, the role of Vitamin E as a prostate cancer reducing factor was established. In this study there was a 32% decrease in prostate cancer incidence and 41% decrease in prostate cancer mortality in people receiving Vitamin E supplements when compared to controls.

Breast Cancer:
In Japan, people consume Tofu, a soya product. It contains isoflavones that moderate the estrogen receptors in the body such as breast tissue. The incidence of breast cancer is low in Japan when compared to Western women; only 1/4th of the mortality rate of Western women. Japanese women's low fat diet, high fish consumption and drinking green tea also decrease their breast cancer risk.

One case control study found that regular consumption of soy foods was associated with a marked decrease in breast cancer risk in premenopausal women. No effect in post-menopausal women.

A Japanese case-control study also found that tofu intake (3 times/wk compared with less than 3 times/wk) was associated with decreased risk of breast cancer in premenopausal women. Again, soy intake was not protective against post-menopausal breast cancer.

In one study conducted in America, the relation between soy intake and breast cancer risk found that tofu consumption was protective in both premenopausal and post menopausal Asian women.

Lung Cancer:
Lung cancer risk is substantially decreased by a variety of carotenoids. Carotenoids act as antioxidants and thus minimize cell damage.

One study in Boston focused on the effect of different types of carotenoids on lung cancer risk. It was observed that lung cancer risk was significantly lower in subjects who consumed a diet high in a variety of carotenoids. This was especially true with non-smokers who had 63% less risk.

One study conducted in Hawaii reported further evidence for a protective effect from certain carotenoids against lung cancer and that greater protection was afforded by consuming a variety of vegetables compared to only foods rich in a particular carotenoid.

Stomach Cancer:
Nitrates in food and other preservatives added to food including meat are converted into 'nitrites' in the human stomach. The nitrites undergo nitrosation to form 'nitrosamines' and 'nitrosamides'. This increases the risk of stomach cancer in people eating vegetables from nitrate rich soil.

In one study, Vitamin C appeared to protect against the risk of stomach cancer by inhibiting formation of nitrates in stomach.

Cancer of the stomach is 5 times more common in Japanese people compared to Western populations. When Japanese people migrated to the United States, they progressively acquired the low incidence of the US due to changes in their diets.

In one study conducted in Hawaii that involved both Japanese and Caucasians, the stomach cancer risk was associated with consumption of rice, pickled vegetables, and dried/salted fish, and a negative association with vitamin C intake.

One ecological study in Belgium showed a relation between the nitrate and salt consumption and stomach cancer. The analysis of this model showed that the significance of nitrate as a risk factor for stomach cancer mortality increased markedly with higher sodium levels.

Dietary habits and stomach cancer risk was studied in Shanghai, China. According to this study, risks of stomach cancer were inversely associated with high consumption of several food groups, including fresh vegetables and fruits, poultry, eggs, plant oil, and some nutrients such as protein, fat, fiber, tea and antioxidant vitamins.

By contrast, risks increased with increasing consumption of dietary carbohydrates, frequent consumption of preserved, salty or fried foods and hot soup/porridge, with irregular meals, speed eating and binge eating. This provides evidence that diet plays a major role in stomach cancer risk.

No single food can completely prevent cancer but a balanced combination of different groups can help. Appropriate diet can prevent 3-4 million cancers each year. 

An understanding of asbestos is necessary before we try to understand mesothelioma lung cancer. Asbestos, a natural fibrous mineral, used commonly in construction process and manufacturing industries is detrimental to human health. Continuous inhalation of its fibers enhances the susceptibility to respiratory disorders and can lead to many dangerous diseases. A leading example of such dangerous disease is Mesothelioma lung cancer. Actually, mesothelioma lung cancer is misnomer because mesothelioma cancers affect the lining of lungs (pleura) and abdomen and not the lungs. Since mesothelioma cancers mostly affect the lining of the lungs, it is generally called mesothelioma lung cancer. The workers who had worked in industries such as shipbuilding, asbestos mining, and asbestos production are vulnerable to mesothelioma cancers.

Mesothelioma and the Role of Carcinogens:

What is mesothelioma cancer and how does the lining of the lung become cancerous? Cancer is a tumor that is malignant in nature. Tumor is formed when there is abnormal cell division and cell multiplication in the cancerous cells. Exposure to carcinogens or cancer-causing material like cigarette smoke, asbestos and silica dust is instrumental in this abnormal cell division and formation of tumor.

Mesothelioma cancer is directly linked to asbestos exposure. However, those already exposed to asbestos have a greater chance of developing lung cancer if they are exposed to other carcinogens such as cigarette smoke. A study reports that the workers with a history of asbestos exposure and cigarette smoke are more prone to lung cancer than the non-smokers and those with no history of asbestos exposure.

Complications Associated with Mesothelioma Cancer:

Normally, the latency stage for asbestos-related diseases in general and mesothelioma cancers of the lining of lung in particular, 20-50 years, which makes detection of Mesothelioma a complicated issue. This situation is further aggravated particularly where the worker is also addicted to cigarette smoking. By the time, the disease shows its symptoms, a considerable exposure to additional carcinogens linked to cigarette smoking has already taken place. This makes a worker more vulnerable to lung cancer besides the vulnerability to mesothelioma cancers.

Mesothelioma Cancers and Legal Redress:

The Government is conscious of the ill effects of asbestos exposure and the seriousness of mesothelioma cancer. The employees working in factories with significant risk of asbestos exposure are eligible for Mesothelioma compensation, if the exposure is the cause of Mesothelioma. There has been a spate of lawsuits for seeking compensation for mesothelioma and lung cancers. In many cases, the courts have awarded heavy sums as compensation against the asbestos manufacturing companies. 

Cancer is a very serious illness. This dreaded disease has caused many deaths; cancer is a disease that’s characterized by uncontrollable cell division and the danger of these mutant cells to invade the neighboring healthy cells and infect them. There are many types of cancer and most of them are deadly which can cause death, while there are some treatments available; there has been no known cure that’s potently effective just yet. Some treatments can kill the cancerous cells while some control the symptoms such as pain. Millions every year gets afflicted with different types of cancer and millions more die every year all over the world. Cancer has been a serious predicament in the medical world and there are concerns on the probability of finding a cure soon.

There are some major efforts being done to correct this but funds have been dwindling making these researches an effort that needs the aid of many people. Many foundations, colleges and other medical groups are doing intensive scientific endeavors to understand fully the development of cancer and what possible treatments, therapies and cure could be done to prevent cancer and its growth. They are called cancer research. In cancer research they discover new methods of treating cancer with the development of new technology and new discoveries about the disease. With proper funding, cancer researches would be able to flourish and hopefully find the perfect cure.

Many organizations have been doing their best to help fund this research facilities, doing fund raising projects and programs for public awareness. It is essential for the public to take notice of this programs because anyone from anywhere can be afflicted with cancer. Gradually, more and more people have found ways in doing both, raising funds for cancer and spreading awareness. When doing such, you hit the head of a nail twice making it more beneficial for cancer victims. Any method is appreciated as long as it spread awareness and help bring in money to aid cancer research. The current popular method is by selling cancer wristbands, which are inscribed with inspiring and informing statements.

Cancer wristbands have been the craze lately, many are wearing them because they are cool and fashionable and yet they help out in finding a cure for cancer. Remember the ribbons everybody used to wear for AIDS. Cancer Wristbands now are what the AIDS ribbons were then. This stretchy cancer wristbands, usually made from either from rubber or silicone, are a great way to do fundraising. They are one size fits all and don’t cost too much. There is a 100 percent profit in cancer wristbands, which may be donated to cancer researches and also boost cancer awareness. In doing so, you not only get a cool looking cancer wristband, you are also helping out the countless cancer victims all over the world.

Many say that this trend started out when Lance Armstrong came out yellow “LiveStrong” wristband to promote and fund cancer research. That promotion had all the right ingredients to capture the people’s interest. Present was the revered American icon asking the people for help, the item was very affordable, was a good conversation peace and it showed that if you were wearing it, you were concerned about other people and their needs. It was also for a cause everyone wanted to help in and deserved all the help t can get. Soon enough, everyone was wearing them, from high profile people, to entertainers with big names straight to the president.

After that, many cancer wristbands went into the market spreading the word, many organizations joined the bandwagon and produced their own cancer wristbands. It has come to be that the color of the cancer wristband represented which type of cancer was to be benefited; for example, pink bracelets were in aid for breast cancer. Messages and statements would be inscribed in the bracelets empowering the knowledge of the people about cancer and tugging their hearts and the hearts of others to help out for the worthy cause.

Cancer wristbands are not only cool, they also help out, many small organizations can help out by browsing the internet and order them from reputable manufacturers who pledge assistance for every cancer wristband you purchase. You may also do your own fundraising; some sites offer very low prices for wholesale purchases so that you can sell them at a markup price so you can have earnings to donate to research facilities. Be aware, support cancer wristbands to help cancer research.

BREAST CANCER

Posted by Vanhoten | 7:31 PM | | 0 comments »

occurs when cells in the breast begin to grow out of control enabling them to invade nearby tissues or spread throughout the body. Collections of these out of control tissues are called tumors. However, not all breast tumors are considered cancerous since certain types of large cells just cannot be spread or threaten a person’s life and this kind of tumor is called benign tumor. On the other hand, the tumors that can spread all throughout the body or invade nearby tissues are considered cancerous cells and are malignant. Cancer cells usually comes from either ducts or glands in the breast that is why it may take months or even years for a tumor to be notice in the breast. Breast tumors are screened with the use of mammograms that are rather accurate in screening tumor or cancer cells.

Women are much prone to develop breast cancer that men. Only 1% to 2% of men have been known to have cases of breast cancer. The early onset of menstruation in women at the age of 12 increases the risk for a breast cancer on the other hand an early menopausal period may reduce the risk of breast cancer. The risk for women to have breast cancer increases with age in fact a study shows that women over 50 are more likely to develop breast cancer. Nevertheless, the incidence of breast cancer among younger women is also increasing in an alarming rate that is why more women of ages 20s to 30s have subjected themselves to be diagnosed.
Breast cancer is not only acquired but also can be inherited. For women who have genetic mutation such as BRCA1 or BRCA2 has an 80% risk of developing breast cancer. Women who have first-degree relative diagnosed to have breast cancer increase their risk of also acquiring breast cancer. Moreover, women with first-degree relative that are diagnosed to have breast cancer before menopause increase the risk for them in acquiring breast cancer.

Some factors contribute to the occurrence of breast cancer and these are as follows: smoking, alcohol and radiation exposure. Women who are smoking will increase their chances to have breast cancer. Aside from that, high intakes of alcohol have been found to be a source of breast cancer. Radiation exposure is another factor that contributes to breast cancer. Studies have shown that women as well as children who have undergone high-dose radiation therapy have a much higher chance of having breast cancer. 

By now you should be familiar with the yellow 'LiveStrong' rubber cancer awareness bracelets. They were popularized by seven-time Tour de France cycling champion and cancer survivor Lance Armstrong. The money from their proceeds goes for cancer research.

If he has planning to pitchfork cancer awareness into society's consciousness, Lance Armstrong has done a really good job. His rubber bracelets are ubiquitous today, an ever present awareness tool for cancer, and a fund-raising tool for cancer research.

Among cancer awareness bracelets, next to Armstrong's rubber wristbands come the breast cancer awareness bracelets. However, unlike the 'LiveStrong' rubber band bracelets, these breast cancer awareness bracelets come in different colors. The most popular color for breast cancer awareness bracelets is pink.

But why pink? There is a story behind it: Charlotte Haley, a 68-year-old woman, began making and distributing peach ribbons in the 1990s with cards that read: "The National Cancer Institute annual budget is $1.8 billion, only 5 percent goes for cancer prevention. Help us wake up our legislators and America by wearing this ribbon." Haley's daughter, sister and grandmother had breast cancer. Self magazine wanted to use Haley's ribbon but she refused saying they were too commercial. The magazine came up with another color then -- pink. Focus groups say pink is 'soothing, comforting and healing.' Soon the pink ribbon became the worldwide symbol for breast cancer, and Charlotte Haley's peach ribbon was history.

The National Breast Cancer Foundation, Inc. says that more than 211,000 women will be diagnosed with breast cancer in America in 2005. Of these 43,300 will die. One woman in eight either has or will develop breast cancer in her lifetime. In addition, 1,600 men will be diagnosed with breast cancer and 400 will die this year.

However, the breast cancer awareness bracelets can come in all colors, a rainbow of them, depending on the organization or charity selling them. These bracelets usually have some message, such as 'Support Breast Cancer Research And Education' stamped on them.

Well, the breast cancer awareness bracelets needn't be made of rubber or silicone either. The bracelets can be made of pearl, or cats eye, or metal, or any other suitable material. There are even stainless steel breast cancer awareness bracelets! The difference between them is, of course, the price. The rubber ones would sell for around $1 a piece. The metal ones would sell higher. Some pearl breast cancer awareness bracelets sell for around $30 a piece. Such bracelets serve two purposes -- they are jewelry and also spread the message of charity and breast cancer research.

The advantage with rubber breast cancer awareness bracelets, apart from the price, is that they are infinitely customizable. Yes, you can order them in any color and with any message stamped on them. You needn't take them off while washing or playing -- they are all-weather bracelets. And you don't have to worry about losing them, unlike the pearl or cats eye ones.

The rubber breast cancer awareness bracelets can be ordered in bulk or bought in packets of a dozen or so from many Web sites.


About the author:
Shannan Barrett analyzes why breast cancer awareness bracelets are becoming ubiquitous, and why they come mostly in pink color. Learn more about breast cancer at http://www.a1-awareness-bracelets.com/breast-cancer-awareness-bracelet.html

Prostate cancer sun and vitamin D

Posted by Vanhoten | 7:38 PM | | 0 comments »

Cancer Centres in USA compared the lifetime sun exposure in men with advanced prostate cancer and men without disease and they suggest that men who had spent more time in the sun they lives were with low risk of prostate cancer.

New studies in prostate cancer indicate that the men who spent more time in the sun in their live usually can reduce prostate cancer in about 50%

About the above point shown that the prostate uses Vitamin D to promote the normal growth of prostate cells and in consequence to slow the spread of prostate cancer cells to others parts of the body.

Sun exposure prevent prostate cancer and the new research suggest vitamin D in supplement may be a safer option today for men.

Previous studies have shown that many places which long winter like Canada and North America men do not adsorb Vitamin D and others nutrients.

In Canada men do not adsorb vitamin D in consequence one of the seven can develop prostate cancer in their lives;
USA new researches indicate that one of the five men can develop prostate cancer.

Researchers shown that vitamin D has many micronutrients promote and prevent the prostate cancer in men.


About the author:
Hector Milla; editor of the cancer -10.com and you can find more articles about prostate cancer in http://www.cancer-10.com, or heart disease symptom information visiting http://www.heartdiseasesympton.com ,you can reproduce this article in your web site or ezine articles always mention above the author article.